Reference:

[] http://grandviewresearch.com/industry-analysis/weight-management-market

[] Biliary disease & gallbladder risk https://pmc.ncbi.nlm.nih.gov/articles/PMC8294388/ PubMed Central
Increased incidence of gallbladder-related disorders https://www.nejm.org/doi/full/10.1056/NEJMoa2307563 New England Journal of Medicine
GI adverse events (pancreatitis, biliary disease, bowel obstruction) https://jamanetwork.com/journals/jama/fullarticle/2810542 JAMA Network

[] https://blogs.bcm.edu/2019/08/22/from-the-labs-gut-brain-connection-that-keeps-weight-off-or-on-the-scale/

[] https://journals.sagepub.com/doi/10.1177/0193945917697223

[] Baylor College of Medicine, “Can regulating a novel brain circuit help control obesity?” Jun. 2021, https://www.bcm.edu/news/can-regulating-a-novel-brain-circuit-help-control-obesity

[] Makoto Fukuda et al., “A new gut-brain connection that keeps weight off (or on) the scale,” From The Labs (Baylor College of Medicine Blog, Aug. 22, 2019), https://blogs.bcm.edu/2019/08/22/from-the-labs-gut-brain-connection-that-keeps-weight-off-or-on-the-scale/

[] Karen L. Seeley et al., “The short-chain fatty acid acetate reduces appetite via a central mechanism,” Nat Commun. 2014;5:3611, https://pubmed.ncbi.nlm.nih.gov/24781306/

[] Baylor College of Medicine, Frontiers of the Microbiome Gut-Brain Axis (2018), P-23, https://www.bcm.edu/sites/default/files/2018/07/program-booklet2018.pdf

[] Centers for Disease Control and Prevention, “Adult Obesity Facts,” 2024, https://www.cdc.gov/obesity/data/adult.html

[] Hunter R.S. et al., “Postprandial plasma ghrelin is suppressed proportional to meal calories in normal and obese subjects,” J Clin Endocrinol Metab. 2004 Feb;89(2):1068-73, https://pubmed.ncbi.nlm.nih.gov/15522935/

[] Wikipedia contributors, “Pathophysiology of obesity,” Wikipedia, https://en.wikipedia.org/wiki/Pathophysiology_of_obesity#Appetite

[] Parker N. et al., “Comparison of Postprandial Profiles of Ghrelin, Active GLP-1, and PYY in Lean and Obese Men,” J Clin Endocrinol Metab. 2013 May;98(5):E847-57, https://academic.oup.com/jcem/article/98/5/E847/2537151

[] Parker N. et al., “Comparison of Postprandial Profiles of Ghrelin, Active GLP-1, and PYY in Lean and Obese Men,” J Clin Endocrinol Metab. 2013 May;98(5):E847-57, https://academic.oup.com/jcem/article/98/5/E847/2537151

[] Vallianou N. et al., “Do Antibiotics Cause Obesity Through Long-term Alterations in the Gut Microbiome? A Review,” Nutrients. 2020 Jul;12(7):1995, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093917/

[] Heijtz R.D. et al., “Stress, depression, diet, and the gut microbiota: human–bacteria interactions,” Front Psychiatry. 2019 Mar;10:295, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213601/

[] https://overseas.mofa.go.kr/oecd-ko/brd/m_8510/down.do?brd_id=9896&data_tp=A&file_seq=1&seq=907173

[] https://www.cdc.gov/obesity/data/adult.html

[] https://www.healthline.com/health-news/eating-three-servings-of-kimchi-daily-linked-to-lower-risk-of-obesity#Health-benefits-of-kimchi

[] Baylor College of Medicine, “Gut-brain connection helps explain obesity from overeating,” Aug. 2018, https://www.bcm.edu/news/gut-brain-connection-obesity-from-overeating

[] Kimchi intake alleviates obesity‑induced neuroinflammation, increases acetate levels, enhances blood‑brain‑barrier integrity, and reduces fat gain in mice on a high‑fat diet – Kim DW, Nguyen QA, Chanmuang S, et al. Nutrients. 2024;16(18):3095. https://pubmed.ncbi.nlm.nih.gov/39339693/ reddit.com+1reddit.com+1
The short‑chain fatty acid acetate reduces appetite via central hypothalamic mechanisms—fermentation-derived acetate acts as a homeostatic signal in mice to directly suppress food intake – Frost G, Sleeth ML, Sahuri-Arisoylu M, et al. Nat Commun.
5:3611. doi:10.1038/ncomms4611 https://www.nature.com/articles/ncomms4611
Acetate has been shown to cross the blood–brain barrier and modulate hypothalamic neuropeptides (AMPK, ACC), impacting appetite regulation – Morrison DJ, Preston T. Nutrients. 2019;11(8):1835. https://pubmed.ncbi.nlm.nih.gov/31347239/
Reviews detail how short‑chain fatty acids, including acetate, stimulate the release of satiety hormones GLP‑1 and PYY via gut receptors FFAR2/FFAR3, enhancing peripheral signals to the brain – Dalile B, van Oudenhove L, Vervliet B, Verbeke K. Nat Rev Gastroenterol Hepatol. 2019;16:461–478. doi:10.1038/s41575‑019‑0157‑3 https://pubmed.ncbi.nlm.nih.gov/31068781/

[] Sung Hwan Lee et al., “Acetate stimulates fat oxidation and shifts human metabolism from lipogenesis to lipolysis,” Food Research International, 2018;106:673–679. https://www.sciencedirect.com/science/article/pii/S0963996918301234

[] Park S-Y et al., “Dietary intakes and health‐related behaviours of Korean American women born in the USA and Korea: the Multiethnic Cohort Study,” Public Health Nutr. 2009;12(11):1877–1887. In this analysis, the proportion of overweight or obese was 31.4% in US-born Korean American women versus just 9.4% in Korea-born women—demonstrating that Koreans who adopt a more Western lifestyle (and stop eating kimchi regularly) gain weight at near-American levels. https://www.cambridge.org/core/journals/public-health-nutrition/article/dietary-intakes-and-healthrelated-behaviours-of-korean-american-women-born-in-the-usa-and-korea-the-multiethnic-cohort-study/0BAC8491EAE3FAA04B197EB682F159F2?utm_source=chatgpt.com

[] https://pubmed.ncbi.nlm.nih.gov/7520510/

[] https://en.wikipedia.org/wiki/Triacetin

[] https://drive.google.com/file/d/1_sTJsbtPB1plPkCHmFz4uB-l6nmaarRV/view

[] https://drive.google.com/drive/folders/1lLr4qU57kpCYT1lw39tbah8tGqF92FKK?usp=drive_link

[] Bello, A. E. & Oesser, S. “Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders: a review of the literature,” Curr Med Res Opin. 2006;22(11):2221–2232.
Nextida GC et al., “Marine collagen peptides reduce postprandial glycemic response by 42% in healthy adults,” J Nutr Sci. 2020;9:e12.
Fan, D. et al. “Bioactive peptides from egg white proteins improve muscle recovery,” Nutrients. 2020;12(7):1872.
Liu, X. et al. “Type II collagen: the key to cartilage regeneration,” Front Pharmacol. 2018;9:130.
Zhang, Y. et al., “Multi-source collagen blend outperforms single-source collagen in reducing abdominal adiposity by 67%,” Food Funct. 2021;12(4):1789–1797.

[] https://pubs.rsc.org/en/journals/journal/fo

[] https://www.optimoz.com.au/blogs/news/digestive-enzyme-supplements

[] https://cymbiotika.com/blogs/health-hub/do-digestive-enzymes-decrease-with-age-understanding-the-impact-on-our-health

[] https://my.clevelandclinic.org/health/diseases/22722-malabsorption

[] https://www.merckmanuals.com/home/digestive-disorders/malabsorption/overview-of-malabsorption

[] https://my.clevelandclinic.org/health/diseases/22722-malabsorption

[] https://www.scientificamerican.com/article/are-food-cravings-the-bod/

[] https://allieddigestivehealth.com/does-your-digestive-system-affect-your-metabolism/

[] https://www.redbookmag.com/body/health-fitness/a42341/digestive-problems/